LC553 10ml x 553mg/ml/vial

1. Core Identity & Mechanism

• Stimulates Tissue Regeneration: Activates fibroblasts, mesenchymal stem cells (MSCs), and endothelial cells to promote proliferation, migration, and extracellular matrix (ECM) synthesis (e.g., collagen, elastin).
• Metabolic Regulation: Enhances insulin sensitivity, promotes lipolysis (fat breakdown), and inhibits lipid accumulation in hepatic and adipose tissues.
• Anti-Inflammatory & Antioxidant Effects: Suppresses pro-inflammatory cytokines (TNF-α, IL-6) and upregulates antioxidant enzymes (SOD, CAT), reducing oxidative stress and creating a favorable microenvironment for repair.
• Low Off-Target Activity: Designed to bind selectively to receptors on damaged/activated cells, minimizing impact on healthy tissues.

2. Primary Research & Functional Benefits

• Tissue Repair & Regenerative Medicine (Core Application)

  LC553 is widely used in preclinical research for:

  • Musculoskeletal Repair: Accelerates healing of tendons, ligaments, muscles, and bone fractures by stimulating MSC differentiation and angiogenesis (new blood vessel formation)—ideal for sports injury, post-surgical repair, or osteoarthritis models.
  • Skin Regeneration: Promotes collagen synthesis, epidermal cell turnover, and wound closure, making it a valuable tool for wound healing (acute/chronic wounds) and anti-aging skin research (reducing wrinkles, improving elasticity).
  • Organ Repair: Shows potential in preclinical models of liver, kidney, and cardiac injury by reducing fibrosis and enhancing parenchymal cell regeneration.
• Metabolic Disorder Research

  In metabolic studies, LC553 exhibits value for:

  • Type 2 Diabetes (T2D): Improves glucose uptake in skeletal muscle and adipose tissue, reduces hepatic gluconeogenesis, and enhances insulin signaling—relevant for insulin resistance and T2D pathway research.
  • Obesity & NAFLD: Inhibits adipocyte hypertrophy (fat cell enlargement), promotes lipolysis, and reduces liver fat accumulation—suitable for obesity and non-alcoholic fatty liver disease (NAFLD) models.
• Anti-Aging & Cellular Health Research

  LC553 supports anti-aging studies by:

  • Reducing cellular senescence: Inhibits the accumulation of senescent cells (aged/damaged cells) and improves mitochondrial function.
  • Restoring tissue function: Reverses age-related decline in muscle mass (sarcopenia), skin elasticity, and metabolic efficiency in animal models.
• Inflammatory Disease Research

  Preliminary data indicates utility for:

  • Autoimmune Disorders: Modulates immune cell activity to reduce chronic inflammation (e.g., rheumatoid arthritis, psoriasis models).
  • Post-Injury Inflammation: Accelerates resolution of inflammation after tissue damage, preventing excessive scarring (fibrosis).