Botulinum toxin 100iu/1vials

1. Core Identity & Mechanism

2. Primary Therapeutic Benefits (Clinical Applications)

• Neuromuscular Disorder Treatment
  • Reduces muscle spasticity: Used to treat conditions like cervical dystonia (neck muscle spasms), blepharospasm (uncontrolled eyelid closure), strabismus (crossed eyes), and limb spasticity (e.g., post-stroke, cerebral palsy).
  • Relieves dystonia: Targets involuntary muscle contractions in the face, neck, or extremities, improving mobility and reducing pain.
• Pain Management
  • Migraine prevention: Approved for chronic migraine (≥15 headaches/month) by blocking pain signaling pathways and reducing muscle tension in the head/neck.
  • Neuropathic pain relief: Alleviates pain from conditions like trigeminal neuralgia, post-herpetic neuralgia, and myofascial pain syndrome by inhibiting neurotransmitter release involved in pain perception.
• Gastrointestinal & Urological Disorders
  • Treats overactive bladder (OAB): Relaxes bladder detrusor muscle, reducing urinary frequency, urgency, and incontinence.
  • Manages chronic constipation: Improves colonic motility in patients with neurogenic bowel dysfunction.
  • Relieves esophageal achalasia: Dilates the lower esophageal sphincter to facilitate food passage.
• Dermatological Therapeutics
  • Reduces hyperhidrosis: Blocks sweat gland innervation, providing long-term relief from excessive underarm, palm, or plantar sweating (hyperhidrosis).
  • Treats facial synkinesis: Improves facial muscle coordination after Bell’s palsy or facial nerve injury.

3. Cosmetic Benefits (Aesthetic Applications)

• Wrinkle Reduction (Most Common Use)
  • Targets dynamic wrinkles (caused by repeated muscle movement): Forehead lines, glabellar lines (“11” lines between eyebrows), crow’s feet (around eyes), and perioral lines (around the mouth).
  • Mechanism: Temporarily relaxes facial muscles, smoothing existing wrinkles and preventing new ones from forming.
• Facial Contouring
  • Jawline slimming: Reduces masseter muscle size for a more slender facial profile.
  • Brow lift: Elevates the lateral brow by relaxing downward-pulling muscles.
  • Neck rejuvenation: Improves “turkey neck” by relaxing platysma muscle bands.

4. Research Applications

• Neurobiology research: Used to study neuromuscular junction function, neurotransmitter release, and nerve regeneration.
• Drug development: Investigated as a potential treatment for neurodegenerative diseases (e.g., Alzheimer’s, Parkinson’s) and psychiatric conditions (e.g., depression, obsessive-compulsive disorder) by modulating neural circuits.
• Tissue engineering: Explored for controlled muscle relaxation in reconstructive surgery models.